Elucidating the role of androgen receptor in breast cancer
Up to this date only 13 migraine-related genes were known and now a study of proves the contribution of these 10 genes and adds 28 more to the candidate list.
In the international work, focused on the analysis of common genetic migraine variants on people, there is the participation of Professor Bru Cormand and the collaborator Cèlia Sintas, from the Institute of Biomedicine of the University of Barcelona (IBUB.
Marta Cascante with Premi Antoni Caparrós for the best knowledge transfer project, and Dr.
Xavier Barril with Premi Senén Vilaró for the best innovation company.
The study has been published in the prestigious journal Nature Chemistry, on the cover.
The Premis del Consell Social i de la Fundació Bosch i Gimpera awarded IBUB researchers: Dr.
Professor Xavier Barril tells that “All current methods aiming at predicting whether a particular molecule will bind a target protein are based upon affinity issues, this is, the thermodynamic stability of the complex.
Udaya Pratap Singh, Drug Design and Discovery Laboratory Department of Pharmaceutical Sciences, Sam Higginbottom University of Agriculture, Technology and Sci, ALLAHABAD, Uttar Pradesh- 211009 Sree Chitra Tirunal Institute for Medical Sciences & Technology, Thiruvananthapuram, INDIA , CHITHIRA, TC-38/1773, No:95, Kailas Nagar, Poojappura, Thiruvananthapuram, KERALA , Thiruvananthapuram, Kerala- 695012 University Department of Pharmacceutical Sciences, Utkal University, Vani Vihar., University Department of Pharmaceutical Sciences, Utkal University, Vani Vihar.
Therefore this discovery was chosen as the study with the highest impact in the main conference on bone diseases worldwide, from the American Society for Bone and Mineral Research), now published in the prestigious journal IBUB has opened a call addressed to students willing to get initiated in biomedical research, within any of the IBUB laboratories.
Six fellowships are opened for students showing suitable skills to eventually become candidates to join Ph. programs within the Biomedicine research field during the academic year 2017-2018.
Opitz (University of Utah, United States), Giovanni Neri (Catholic University of the Sacred Heart, Italy) and a wide group of experts of the Center for Genomic Regulation (CRG) and the Department of Clinical and Molecular Genetics of the University Hospital Vall d’Hebron (VHIR). Martinez-Estrada, are developing basic biomedical research projects in cardiology with the support of Fundació la Marató de TV3. Subjects such as cardiac regeneration, the role of inflammation, cardiomiokines or heart development will be discussed at the symposium. A team led by researchers of the Institute of Biomedicine of the University of Barcelona (IBUB) and the Research Institute of the Hospital de la Santa Creu i Sant Pau (IIB Sant Pau) shows for the first time, the three-dimensional structure of the homodimeric androgen receptor ligand-binding domain, a structure that eluded researchers for years.
The research project on identifying new therapeutic targets to fight the mechanism of tumor progression, leaded by Marçal Pastor-Anglada, IBUB Director, have been awarded by the Fundación Ramón Areces. The mini-symposium on 3 March will provide an overview of this research, complemented by contributions from international experts in experimental research on cardiology such as Dr. Bayes-Genis, from the Hospital Germans Trias i Pujol, and Dr. This new structure of the nuclear receptor allows explaining more than forty mutations related to prostate cancer, one of the most common worldwide and especially in Catalonia, as well as known developing disorders such as the androgen insensitivity syndromes.
Search for elucidating the role of androgen receptor in breast cancer:
The Valorization and Licensing Unit of the Bosch i Gimpera Foundation has supported the research group with the procedures associated with this protection.